🔬 剪接因子 CPSF1 靶基因疾病富集分析

疾病名称	Overlap	P-value	富集倍数	相关靶基因
neurodegenerative disease	185/422	0.003167	1.1x	RBM15B, SF3B1, SRSF1, SAMD4B, RBM22, HNRNPK, RBM17, PRPF19, DDX17, PABPC1, MBNL1, BUD13, WBP4, DHX30, LUC7L3, SART3, CTNNBL1, EIF4B, LSM4, SNRNP70
autism	7/9	0.023998	1.95x	DHX30, PPIL2, SNRPN, THOC2, NONO, FMR1, XRN2
hemorrhoid	4/4	0.025083	2.5x	SFMBT1, CCNL1, CCAR2, SND1
coronary atherosclerosis	6/8	0.048362	1.88x	SF3A3, GPATCH3, ADAR, AGO2, CCNL1, BUD13
Gastric Adenoma	14/24	0.049502	1.46x	ZCCHC8, FUS, NUMA1, ZRSR2, THRAP3, SPEN, SFPQ, ZMYM3, QKI, DDX6, DDX3X, SND1, PRCC, CPEB3

💡 说明：
• Overlap: 靶基因中与该疾病相关的基因数 / 数据库中该疾病总关联基因数
• P-value: 超几何检验显著性，越小代表富集越显著
• 富集倍数: 实际关联数 / 期望关联数，>1 表示富集