🔬 剪接因子 DDX5 靶基因疾病富集分析

疾病名称	Overlap	P-value	富集倍数	相关靶基因
phototoxic dermatitis	3/5	0.013454	5.06x	RALY, ZC3H18, CPEB2
T-Cell Prolymphocytic Leukemia	4/9	0.014485	3.75x	SND1, EWSR1, SPEN, PABPC1
Global developmental delay	6/20	0.022662	2.53x	PABPC1, UPF1, SNRNP70, DHX30, AAR2, DDX5
gliomatosis cerebri	5/15	0.023736	2.81x	NUMA1, EWSR1, SND1, SPEN, DDX5
lipoma	3/6	0.024622	4.22x	FUS, EWSR1, AAR2
mixed liposarcoma	3/6	0.024622	4.22x	SND1, EWSR1, FUS
Cachexia	2/3	0.038465	5.62x	HNRNPU, ZC3H18
Atypical behavior	2/3	0.038465	5.62x	UPF1, PABPC1
gastric ulcer	2/3	0.038465	5.62x	RBM33, SND1
autoimmune disorder of musculoskeletal system	2/3	0.038465	5.62x	RBM33, CPEB2
metaplastic breast carcinoma	6/23	0.044078	2.2x	FUS, PABPC1, SPEN, SND1, SRSF2, DDX5

💡 说明：
• Overlap: 靶基因中与该疾病相关的基因数 / 数据库中该疾病总关联基因数
• P-value: 超几何检验显著性，越小代表富集越显著
• 富集倍数: 实际关联数 / 期望关联数，>1 表示富集