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🔬 剪接因子 HNRNPD 靶基因疾病富集分析
| 疾病名称 | Overlap | P-value | 富集倍数 | 相关靶基因 |
|---|---|---|---|---|
| hepatocellular carcinoma | 35/113 | 0.000725 | 1.6x | FUS, SF3B1, SRSF1, THRAP3, KHDRBS1, SFPQ, HNRNPK, DDX17, PABPC1, SRSF10, EWSR1, CPSF6, HNRNPA2B1, YBX1, QKI, IGF2BP3, ZCCHC8, HNRNPC, HNRNPA1, PSIP1 |
| brain glioblastoma | 20/53 | 0.000852 | 1.95x | FUS, SF3B1, THRAP3, SFPQ, PABPC1, EWSR1, HNRNPA2B1, QKI, ZCCHC8, PSIP1, FUBP1, NONO, SRSF2, DDX5, SPEN, SRSF3, DDX6, DDX3X, SND1, PRCC |
| Duodenal Adenocarcinoma | 17/43 | 0.001185 | 2.04x | ZCCHC8, FUS, SF3B1, FUBP1, DDX5, SPEN, EWSR1, SFPQ, THRAP3, HNRNPA2B1, PSIP1, QKI, NONO, DDX6, DDX3X, SND1, PRCC |
| non-small cell lung carcinoma | 21/58 | 0.001186 | 1.87x | FUS, SF3B1, THRAP3, SFPQ, EWSR1, HNRNPA2B1, YBX1, QKI, ZCCHC8, PSIP1, NONO, FUBP1, AGO2, SRSF2, DDX5, SPEN, SRSF3, DDX6, DDX3X, SND1 |
| Ovarian Endometrioid Adenocarcinoma with Squamous Differentiation | 19/51 | 0.001407 | 1.93x | FUS, SF3B1, THRAP3, SFPQ, PABPC1, EWSR1, HNRNPA2B1, QKI, ZCCHC8, PSIP1, FUBP1, NONO, SRSF2, SPEN, SRSF3, DDX6, DDX3X, SND1, PRCC |
| thyroid carcinoma | 20/55 | 0.001484 | 1.88x | FUS, SF3B1, THRAP3, SFPQ, PABPC1, EWSR1, HNRNPA2B1, QKI, ZCCHC8, PSIP1, FUBP1, NONO, SRSF2, DDX5, SPEN, SRSF3, DDX6, DDX3X, SND1, PRCC |
| lung carcinoma | 20/55 | 0.001484 | 1.88x | FUS, SF3B1, THRAP3, SFPQ, PABPC1, EWSR1, HNRNPA2B1, QKI, ZCCHC8, PSIP1, FUBP1, NONO, SRSF2, DDX5, SPEN, SRSF3, DDX6, DDX3X, SND1, PRCC |
| skin basal cell carcinoma | 20/55 | 0.001484 | 1.88x | FUS, SF3B1, THRAP3, SFPQ, PABPC1, EWSR1, HNRNPA2B1, QKI, ZCCHC8, PSIP1, FUBP1, NONO, SRSF2, DDX5, SPEN, SRSF3, DDX6, DDX3X, SND1, PRCC |
| carcinoma of liver and intrahepatic biliary tract | 20/55 | 0.001484 | 1.88x | FUS, SF3B1, THRAP3, SFPQ, PABPC1, EWSR1, HNRNPA2B1, QKI, ZCCHC8, PSIP1, FUBP1, NONO, SRSF2, DDX5, SPEN, SRSF3, DDX6, DDX3X, SND1, PRCC |
| bile duct carcinoma | 20/55 | 0.001484 | 1.88x | FUS, SF3B1, THRAP3, SFPQ, PABPC1, EWSR1, HNRNPA2B1, QKI, ZCCHC8, PSIP1, FUBP1, NONO, SRSF2, DDX5, SPEN, SRSF3, DDX6, DDX3X, SND1, PRCC |
| pulmonary large cell neuroendocrine carcinoma | 11/23 | 0.001537 | 2.47x | ZCCHC8, SF3B1, DDX5, THRAP3, SFPQ, HNRNPA2B1, PSIP1, FUBP1, DDX3X, SND1, QKI |
| lung adenocarcinoma | 22/63 | 0.001573 | 1.81x | FUS, SF3B1, THRAP3, SFPQ, PABPC1, EWSR1, HNRNPA2B1, YBX1, QKI, IGF2BP3, ZCCHC8, PSIP1, FUBP1, NONO, SRSF2, DDX5, SPEN, SRSF3, DDX6, DDX3X |
| small cell lung carcinoma | 18/48 | 0.001748 | 1.94x | ZCCHC8, FUS, SF3B1, SRSF2, FUBP1, PABPC1, DDX5, SPEN, EWSR1, SFPQ, HNRNPA2B1, PSIP1, QKI, NONO, DDX6, DDX3X, SND1, PRCC |
| papillary thyroid carcinoma | 18/48 | 0.001748 | 1.94x | ZCCHC8, FUS, SF3B1, SRSF2, FUBP1, PABPC1, THRAP3, SPEN, EWSR1, SFPQ, PSIP1, QKI, SRSF3, NONO, DDX6, DDX3X, SND1, PRCC |
| oral squamous cell carcinoma | 15/37 | 0.001756 | 2.1x | ZCCHC8, SF3B1, FUBP1, PABPC1, DDX5, SPEN, EWSR1, THRAP3, HNRNPA2B1, QKI, NONO, DDX6, DDX3X, SND1, PRCC |
| gastric carcinoma | 20/56 | 0.001928 | 1.85x | FUS, SF3B1, THRAP3, SFPQ, PABPC1, EWSR1, HNRNPA2B1, QKI, ZCCHC8, PSIP1, FUBP1, NONO, SRSF2, DDX5, SPEN, SRSF3, DDX6, DDX3X, SND1, PRCC |
| kidney neoplasm | 18/49 | 0.002307 | 1.9x | FUS, SF3B1, SRSF2, PABPC1, DDX5, SPEN, EWSR1, SFPQ, THRAP3, HNRNPA2B1, PRCC, PSIP1, SRSF3, FUBP1, DDX6, DDX3X, SND1, QKI |
| Gallbladder Adenocarcinoma | 15/38 | 0.002423 | 2.04x | SF3B1, FUS, FUBP1, PABPC1, DDX5, SPEN, SFPQ, THRAP3, HNRNPA2B1, PSIP1, NONO, DDX6, DDX3X, SND1, PRCC |
| lymphoid neoplasm | 20/57 | 0.002482 | 1.81x | FUS, SF3B1, THRAP3, SFPQ, PABPC1, EWSR1, HNRNPA2B1, QKI, ZCCHC8, PSIP1, FUBP1, NONO, SRSF2, DDX5, SPEN, SRSF3, DDX6, DDX3X, SND1, PRCC |
| squamous cell lung carcinoma | 21/61 | 0.002520 | 1.78x | FUS, SF3B1, THRAP3, SFPQ, PABPC1, EWSR1, HNRNPA2B1, QKI, ZCCHC8, PSIP1, FUBP1, NONO, SRSF2, DDX5, SPEN, PSPC1, SRSF3, DDX6, DDX3X, SND1 |
| head and neck squamous cell carcinoma | 21/61 | 0.002520 | 1.78x | FUS, SF3B1, THRAP3, KHDRBS1, SFPQ, PABPC1, EWSR1, HNRNPA2B1, QKI, ZCCHC8, PSIP1, FUBP1, NONO, SRSF2, DDX5, SPEN, SRSF3, DDX6, DDX3X, SND1 |
| urinary bladder carcinoma | 22/65 | 0.002531 | 1.75x | FUS, SF3B1, THRAP3, SFPQ, PABPC1, EWSR1, CWC27, HNRNPA2B1, QKI, IGF2BP3, ZCCHC8, PSIP1, FUBP1, NONO, SRSF2, DDX5, SPEN, SRSF3, DDX6, DDX3X |
| central nervous system primitive neuroectodermal neoplasm | 18/50 | 0.003010 | 1.86x | FUS, SF3B1, SRSF2, FUBP1, PABPC1, DDX5, SPEN, EWSR1, SFPQ, THRAP3, HNRNPA2B1, PRCC, PSIP1, NONO, DDX6, DDX3X, SND1, QKI |
| rectal adenocarcinoma | 20/58 | 0.003163 | 1.78x | FUS, SF3B1, THRAP3, SFPQ, PABPC1, EWSR1, HNRNPA2B1, QKI, ZCCHC8, PSIP1, FUBP1, NONO, SRSF2, DDX5, SPEN, SRSF3, DDX6, DDX3X, SND1, PRCC |
| prostate carcinoma | 23/71 | 0.003874 | 1.67x | FUS, SF3B1, THRAP3, SFPQ, PABPC1, MBNL1, SRSF10, EWSR1, HNRNPA2B1, QKI, ZCCHC8, PSIP1, NONO, FUBP1, GPATCH8, SRSF2, DDX5, SPEN, SRSF3, DDX6 |
| cecum adenocarcinoma | 19/55 | 0.003965 | 1.79x | FUS, SF3B1, THRAP3, SFPQ, PABPC1, EWSR1, HNRNPA2B1, QKI, ZCCHC8, PSIP1, FUBP1, NONO, DDX5, SPEN, SRSF3, DDX6, DDX3X, SND1, PRCC |
| acute myeloid leukemia | 21/63 | 0.003988 | 1.72x | FUS, SF3B1, THRAP3, SFPQ, PABPC1, EWSR1, HNRNPA2B1, IGF2BP3, QKI, ZCCHC8, PSIP1, FUBP1, NONO, SRSF2, DDX5, SPEN, SRSF3, DDX6, DDX3X, SND1 |
| breast carcinoma | 21/63 | 0.003988 | 1.72x | FUS, SF3B1, THRAP3, SFPQ, PABPC1, EWSR1, HNRNPA2B1, QKI, ZCCHC8, PSIP1, FUBP1, NONO, SRSF2, DDX5, SPEN, ZC3H11A, SRSF3, DDX6, DDX3X, SND1 |
| bladder transitional cell carcinoma | 20/59 | 0.003997 | 1.75x | FUS, SF3B1, THRAP3, SFPQ, PABPC1, EWSR1, HNRNPA2B1, QKI, ZCCHC8, PSIP1, FUBP1, NONO, SRSF2, DDX5, SPEN, SRSF3, DDX6, DDX3X, SND1, PRCC |
| colon adenocarcinoma | 20/59 | 0.003997 | 1.75x | FUS, SF3B1, THRAP3, SFPQ, PABPC1, EWSR1, HNRNPA2B1, QKI, ZCCHC8, PSIP1, FUBP1, NONO, SRSF2, DDX5, SPEN, SRSF3, DDX6, DDX3X, SND1, PRCC |
💡 说明：
• Overlap: 靶基因中与该疾病相关的基因数 / 数据库中该疾病总关联基因数
• P-value: 超几何检验显著性，越小代表富集越显著
• 富集倍数: 实际关联数 / 期望关联数，>1 表示富集
• Overlap: 靶基因中与该疾病相关的基因数 / 数据库中该疾病总关联基因数
• P-value: 超几何检验显著性，越小代表富集越显著
• 富集倍数: 实际关联数 / 期望关联数，>1 表示富集