← 返回靶基因列表
🔬 剪接因子 HNRNPM 靶基因疾病富集分析
| 疾病名称 | Overlap | P-value | 富集倍数 | 相关靶基因 |
|---|---|---|---|---|
| Gallbladder Adenocarcinoma | 21/38 | 0.011129 | 1.52x | FUS, SF3B1, ZRSR2, THRAP3, SFPQ, RNF213, PABPC1, HNRNPA2B1, NUMA1, U2AF1, PSIP1, FUBP1, NONO, CPEB3, DDX5, SPEN, RBM10, DDX6, DDX3X, SND1 |
| pulmonary large cell neuroendocrine carcinoma | 14/23 | 0.013010 | 1.67x | ZCCHC8, SF3B1, ZRSR2, THRAP3, DDX5, SFPQ, RBM10, HNRNPA2B1, PSIP1, RNF213, FUBP1, DDX3X, SND1, QKI |
| Duodenal Adenocarcinoma | 23/43 | 0.013222 | 1.47x | FUS, SF3B1, ZRSR2, THRAP3, SFPQ, RNF213, EWSR1, HNRNPA2B1, QKI, ZCCHC8, NUMA1, U2AF1, PSIP1, FUBP1, NONO, CPEB3, DDX5, SPEN, RBM10, DDX6 |
| autism | 7/9 | 0.013521 | 2.14x | DHX30, PPIL2, SNRPN, THOC2, NONO, FMR1, XRN2 |
| hemorrhoid | 4/4 | 0.017172 | 2.75x | SFMBT1, CCNL1, CCAR2, SND1 |
| skin carcinoma | 22/42 | 0.020731 | 1.44x | FUS, SF3B1, ZRSR2, THRAP3, RNF213, PABPC1, EWSR1, HNRNPA2B1, QKI, ZCCHC8, NUMA1, U2AF1, RALY, PSIP1, CPEB3, SPEN, RBM10, SRSF3, DDX6, DDX3X |
| Gastric Adenoma | 14/24 | 0.021166 | 1.6x | ZCCHC8, FUS, NUMA1, ZRSR2, THRAP3, SPEN, SFPQ, RNF213, QKI, DDX6, DDX3X, SND1, PRCC, CPEB3 |
| neurodegenerative disease | 165/422 | 0.026750 | 1.08x | SF3B1, SRSF1, RBM38, DHX38, HNRNPK, RBM17, RBMX2, PRPF19, DDX17, PABPC1, RBPMS, MBNL1, DHX30, LUC7L3, SART3, CTNNBL1, EIF4B, DHX35, LSM4, RALYL |
| melanoma | 27/55 | 0.029623 | 1.35x | FUS, SF3B1, ZRSR2, THRAP3, SFPQ, RNF213, PABPC1, EWSR1, ADAR, YBX1, QKI, ZCCHC8, NUMA1, CDK10, U2AF1, RALY, FUBP1, NONO, CPEB3, SRSF2 |
| lung carcinoma | 27/55 | 0.029623 | 1.35x | FUS, SF3B1, ZRSR2, THRAP3, SFPQ, RNF213, PABPC1, EWSR1, HNRNPA2B1, QKI, ZCCHC8, NUMA1, U2AF1, RALY, PSIP1, FUBP1, NONO, CPEB3, SRSF2, DDX5 |
| papillary thyroid carcinoma | 24/48 | 0.031044 | 1.38x | FUS, SF3B1, ZRSR2, THRAP3, SFPQ, RNF213, PABPC1, EWSR1, QKI, ZCCHC8, NUMA1, U2AF1, PSIP1, FUBP1, NONO, CPEB3, SRSF2, SPEN, RBM10, SRSF3 |
| female breast carcinoma | 18/34 | 0.031599 | 1.46x | NUMA1, FUS, SF3B1, ZRSR2, PABPC1, THRAP3, SPEN, EWSR1, DDX5, RBM10, HNRNPA2B1, PSIP1, RNF213, QKI, DDX3X, SND1, PRCC, CPEB3 |
| oral cavity carcinoma | 21/41 | 0.031843 | 1.41x | FUS, SF3B1, ZRSR2, THRAP3, RNF213, PABPC1, EWSR1, QKI, NUMA1, U2AF1, PSIP1, FUBP1, NONO, CPEB3, SPEN, RBM10, SRSF3, DDX6, DDX3X, SND1 |
| non-small cell lung carcinoma | 28/58 | 0.034552 | 1.33x | FUS, SF3B1, ZRSR2, THRAP3, SFPQ, RNF213, EWSR1, HNRNPA2B1, YBX1, QKI, ZCCHC8, NUMA1, RBM5, U2AF1, ALYREF, PSIP1, NONO, FUBP1, AGO2, SRSF2 |
| hepatocellular carcinoma | 50/113 | 0.035652 | 1.22x | FUS, SF3B1, SRSF1, ZRSR2, THRAP3, SFPQ, KHDRBS1, HNRNPK, RNF213, PRPF19, DDX17, PABPC1, SRSF10, PTBP1, ELAVL1, EWSR1, ADAR, CPSF6, SUGP1, HNRNPA2B1 |
| breast carcinoma | 30/63 | 0.035730 | 1.31x | FUS, SF3B1, ZRSR2, THRAP3, SFPQ, RNF213, PABPC1, EWSR1, ADAR, HNRNPA2B1, QKI, FAM50A, ZCCHC8, NUMA1, U2AF1, RALY, PSIP1, FUBP1, NONO, CPEB3 |
| Ovarian Endometrioid Adenocarcinoma with Squamous Differentiation | 25/51 | 0.036776 | 1.35x | FUS, SF3B1, ZRSR2, THRAP3, SFPQ, RNF213, PABPC1, EWSR1, HNRNPA2B1, QKI, ZCCHC8, NUMA1, U2AF1, PSIP1, FUBP1, NONO, CPEB3, SRSF2, SPEN, RBM10 |
| oral squamous cell carcinoma | 19/37 | 0.039488 | 1.41x | SF3B1, ZRSR2, THRAP3, RNF213, PABPC1, EWSR1, HNRNPA2B1, QKI, ZCCHC8, NUMA1, FUBP1, NONO, DDX5, SPEN, RBM10, DDX6, DDX3X, SND1, PRCC |
| multiple myeloma | 24/49 | 0.040971 | 1.35x | FUS, SF3B1, ZRSR2, THRAP3, RNF213, PABPC1, EWSR1, HNRNPA2B1, QKI, NUMA1, U2AF1, PSIP1, FUBP1, NONO, EFTUD2, CPEB3, SRSF2, DDX5, SPEN, RBM10 |
| kidney neoplasm | 24/49 | 0.040971 | 1.35x | FUS, SF3B1, ZRSR2, THRAP3, SFPQ, RNF213, PABPC1, EWSR1, HNRNPA2B1, QKI, NUMA1, U2AF1, PSIP1, FUBP1, CPEB3, SRSF2, DDX5, SPEN, RBM10, SRSF3 |
| Atypical Meningioma | 11/19 | 0.043248 | 1.59x | FUS, SF3B1, PABPC1, DDX5, RBM10, PSIP1, RNF213, FUBP1, DDX3X, SND1, PRCC |
| pancreatic neuroendocrine tumor | 18/35 | 0.043982 | 1.41x | ZCCHC8, SF3B1, NUMA1, SRSF2, ZRSR2, THRAP3, SPEN, EWSR1, SFPQ, RBM10, HNRNPA2B1, PSIP1, RNF213, QKI, DDX6, SND1, PRCC, CPEB3 |
| neoplasm | 51/117 | 0.046002 | 1.2x | SF3B1, SRSF1, RBM38, DKC1, THRAP3, SFPQ, KHDRBS1, HNRNPK, CPEB1, RNF213, FMR1, MBNL1, ELAVL1, EWSR1, ADAR, SUGP1, HNRNPA2B1, UPF1, YBX1, TIA1 |
| skin angiosarcoma | 3/3 | 0.047634 | 2.75x | SND1, DDX3X, RNF213 |
| gastric ulcer | 3/3 | 0.047634 | 2.75x | RBM33, HNRNPLL, SND1 |
| hypotension | 3/3 | 0.047634 | 2.75x | SNRPA1, ELAVL2, AGGF1 |
| HER2 Positive Breast Carcinoma | 20/40 | 0.047877 | 1.38x | SF3B1, ZRSR2, THRAP3, SFPQ, RNF213, PABPC1, EWSR1, HNRNPA2B1, QKI, ZCCHC8, NUMA1, PSIP1, CPEB3, SRSF2, SPEN, RBM10, DDX6, DDX3X, SND1, PRCC |
💡 说明：
• Overlap: 靶基因中与该疾病相关的基因数 / 数据库中该疾病总关联基因数
• P-value: 超几何检验显著性，越小代表富集越显著
• 富集倍数: 实际关联数 / 期望关联数，>1 表示富集
• Overlap: 靶基因中与该疾病相关的基因数 / 数据库中该疾病总关联基因数
• P-value: 超几何检验显著性，越小代表富集越显著
• 富集倍数: 实际关联数 / 期望关联数，>1 表示富集