🔬 剪接因子 MSI1 靶基因疾病富集分析

疾病名称	Overlap	P-value	富集倍数	相关靶基因
neoplasm	43/117	0.008676	1.35x	NUDT21, SF3B1, SRSF1, RBM38, DKC1, THRAP3, KHDRBS1, SFPQ, HNRNPK, RNF213, CPEB4, PCBP1, FMR1, MBNL1, ELAVL1, ADAR, HNRNPA2B1, UPF1, RBM15, QKI
skin angiosarcoma	3/3	0.020095	3.66x	SND1, DDX3X, RNF213
gastric ulcer	3/3	0.020095	3.66x	RBM33, HNRNPLL, SND1
pulmonary large cell neuroendocrine carcinoma	11/23	0.026104	1.75x	SF3B1, THRAP3, DDX5, SFPQ, RBM10, HNRNPA2B1, RNF213, FUBP1, DDX3X, SND1, QKI
cancer	24/62	0.026836	1.42x	SF3B1, SRSF1, KHDRBS1, SNW1, RNF213, ZC3HAV1, ELAVL1, ADAR, CPSF6, HNRNPA2B1, RBM15, QKI, IGF2BP3, HNRNPC, HNRNPA1, RALY, AGO2, RBMS1, CCAR2, DDX5
Atypical Meningioma	9/19	0.046444	1.74x	FUS, SF3B1, DDX5, RBM10, RNF213, FUBP1, DDX3X, SND1, PABPC1

💡 说明：
• Overlap: 靶基因中与该疾病相关的基因数 / 数据库中该疾病总关联基因数
• P-value: 超几何检验显著性，越小代表富集越显著
• 富集倍数: 实际关联数 / 期望关联数，>1 表示富集