🔬 剪接因子 PABPC4 靶基因疾病富集分析

疾病名称	Overlap	P-value	富集倍数	相关靶基因
dengue disease	81/212	0.001008	1.28x	FUS, SF3B1, NUDT21, SRSF1, HNRNPA3, RBM22, HNRNPK, RBM17, PPIE, PRPF19, PABPC1, SRSF6, HNRNPC, PHF5A, SRSF7, HNRNPA0, XAB2, DDX5, HNRNPD, DDX3X
neurodegenerative disease	140/422	0.008123	1.11x	SF3B1, SRSF1, RBM38, SAMD4B, RBM22, HNRNPK, PRPF38A, MAGOH, RBM17, PRPF19, DDX17, PABPC1, MBNL1, LSM6, LUC7L3, SART3, EIF4B, LSM4, SNRNP70, HNRNPC
hepatocellular carcinoma	43/113	0.026513	1.27x	FUS, SF3B1, SRSF1, THRAP3, KHDRBS1, SFPQ, HNRNPK, PCBP1, SF3B4, PRPF19, DDX17, PABPC1, SRSF10, ELAVL1, EWSR1, ADAR, PPIH, HNRNPA2B1, UPF1, HSPA8
salivary gland adenoid cystic carcinoma	12/24	0.028501	1.67x	NUMA1, SF3B1, FUBP1, DDX5, SPEN, SFPQ, U2AF1, HNRNPA2B1, NONO, DDX6, DDX3X, SND1

💡 说明：
• Overlap: 靶基因中与该疾病相关的基因数 / 数据库中该疾病总关联基因数
• P-value: 超几何检验显著性，越小代表富集越显著
• 富集倍数: 实际关联数 / 期望关联数，>1 表示富集