🔬 剪接因子 PABPC4 靶基因疾病富集分析

疾病名称	Overlap	P-value	富集倍数	相关靶基因
dengue disease	81/212	0.001008	1.28x	CHERP, SRSF3, HNRNPF, SF3A1, SRRM1, RBM22, RBMX, PRPF19, SNRPE, PPIE, HNRNPK, SRSF1, NUDT21, SNRNP40, HNRNPA1, U2AF1, RBM17, ALYREF, SNRPF, SF3B1
neurodegenerative disease	140/422	0.008123	1.11x	SNRNP25, CHERP, SRSF3, MATR3, HNRNPF, SART3, SF3A1, HTATSF1, RBM39, RBM4, SRRM1, ZCRB1, RBM22, RBM27, RBMX, DDX6, PRPF19, ZRANB2, SNRPE, TRA2A
hepatocellular carcinoma	43/113	0.026513	1.27x	NONO, SF3B4, YBX1, HNRNPA2B1, SRSF3, AGO2, RBM15, TARDBP, DDX5, KHDRBS1, PABPC1, FUBP1, SF3B1, QKI, SPEN, HNRNPC, HNRNPD, PPIH, PTBP1, CPSF3
salivary gland adenoid cystic carcinoma	12/24	0.028501	1.67x	NONO, FUBP1, DDX6, DDX3X, HNRNPA2B1, NUMA1, SF3B1, SFPQ, SPEN, SND1, U2AF1, DDX5

💡 说明：
• Overlap: 靶基因中与该疾病相关的基因数 / 数据库中该疾病总关联基因数
• P-value: 超几何检验显著性，越小代表富集越显著
• 富集倍数: 实际关联数 / 期望关联数，>1 表示富集