🧬 基因注释：ACSL5
官方名称：acyl-CoA synthetase long chain family member 5
功能摘要：The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in uterus and spleen, and in trace amounts in normal brain, but has markedly increased levels in malignant gliomas. This gene functions in mediating fatty acid-induced glioma cell growth. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
- CSTF2T 置信度: 2.0
- HNRNPA2B1 置信度: 2.0
- HNRNPC 置信度: 2.0
- HNRNPK 置信度: 2.0
- HNRNPL 置信度: 2.0
- MBNL1 置信度: 2.0
- AQR 置信度: 1.0
- MATR3 置信度: 1.0
- PCBP2 置信度: 1.0
- PRPF8 置信度: 1.0
- Rbm7 置信度: 1.0
- Rnps1 置信度: 1.0
- Sf3b1 置信度: 1.0
- Srsf1 置信度: 1.0
- Srsf7 置信度: 1.0
- TIA1 置信度: 1.0
- Tra2b 置信度: 1.0
- U2af1 置信度: 1.0
- U2af2 置信度: 1.0
- YBX1 置信度: 1.0
该基因暂无关联疾病记录