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🧬 基因注释:ADAM19

📝 官方信息

官方名称:ADAM metallopeptidase domain 19

功能摘要:This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has been demonstrated to be an active metalloproteinase, which may be involved in normal physiological processes such as cell migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. It is proposed to play a role in pathological processes, such as cancer, inflammatory diseases, renal diseases, and Alzheimer's disease. [provided by RefSeq, May 2013].

🎯 作为靶基因的剪接因子
  • HNRNPA2B1 综合评分: 0.350 · 证据 2 条
  • HNRNPC 综合评分: 0.350 · 证据 2 条
  • HNRNPM 综合评分: 0.350 · 证据 2 条
  • MBNL1 综合评分: 0.350 · 证据 2 条
  • QKI 综合评分: 0.350 · 证据 1 条
  • NOVA1 综合评分: 0.324 · 证据 2 条
  • FUS 综合评分: 0.300 · 证据 1 条
  • HNRNPL 综合评分: 0.300 · 证据 2 条
  • PTBP1 综合评分: 0.300 · 证据 2 条
  • RBFOX2 综合评分: 0.300 · 证据 2 条
  • fus 综合评分: 0.300 · 证据 1 条
  • Nova2 综合评分: 0.262 · 证据 1 条
  • RBM10 综合评分: 0.250 · 证据 2 条
  • RBM15 综合评分: 0.250 · 证据 2 条
  • GRSF1 综合评分: 0.212 · 证据 2 条
  • Mbnl2 综合评分: 0.200 · 证据 1 条
  • RBM20 综合评分: 0.162 · 证据 2 条
  • YBX1 综合评分: 0.162 · 证据 1 条
  • MSI1 综合评分: 0.150 · 证据 1 条
  • Srsf1 综合评分: 0.150 · 证据 1 条
🏥 关联疾病

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