🧬 基因注释：ADGRE2
📝 官方信息
官方名称：adhesion G protein-coupled receptor E2
功能摘要：This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor-like domains coupled to a TM7 domain via a mucin-like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains. This gene is situated in a cluster of related genes on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012].
🎯 作为靶基因的剪接因子
- ACIN1 置信度: 2.0
- CSTF2 置信度: 2.0
- EIF4A3 置信度: 2.0
- HNRNPA1 置信度: 2.0
- HNRNPC 置信度: 2.0
- HNRNPL 置信度: 2.0
- PTBP1 置信度: 2.0
- RBM39 置信度: 2.0
- AQR 置信度: 1.0
- NXF1 置信度: 1.0
- PRPF8 置信度: 1.0
- Rbmx 置信度: 1.0
- Rnps1 置信度: 1.0
- SRSF2 置信度: 1.0
- SRSF3 置信度: 1.0
- Srsf1 置信度: 1.0
- Srsf7 置信度: 1.0
- Tardbp 置信度: 1.0
- U2af1 置信度: 1.0
- U2af2 置信度: 1.0
🏥 关联疾病
该基因暂无关联疾病记录