SpliceAtlasDB
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🧬 基因注释:ADGRE3

📝 官方信息

官方名称:adhesion G protein-coupled receptor E3

功能摘要:This gene encodes a member of the class B seven-span transmembrane (TM7) receptor family expressed predominantly by cells of the immune system. Family members are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor (EGF)-like domains coupled to a TM7 domain via a mucin-like spacer domain. This gene is closely linked to the gene encoding egf-like molecule containing mucin-like hormone receptor 2 on chromosome 19. This protein may play a role in myeloid-myeloid interactions during immune and inflammatory responses. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2014].

🎯 作为靶基因的剪接因子
  • Tardbp 综合评分: 0.473 · 证据 1 条
  • FUS 综合评分: 0.444 · 证据 1 条
  • fus 综合评分: 0.444 · 证据 1 条
  • HNRNPA2B1 综合评分: 0.412 · 证据 2 条
  • RBFOX2 综合评分: 0.398 · 证据 2 条
  • MBNL1 综合评分: 0.350 · 证据 2 条
  • EWSR1 综合评分: 0.312 · 证据 2 条
  • HNRNPK 综合评分: 0.300 · 证据 2 条
  • HNRNPU 综合评分: 0.300 · 证据 2 条
  • PTBP1 综合评分: 0.300 · 证据 2 条
  • Rnps1 综合评分: 0.296 · 证据 1 条
  • TIA1 综合评分: 0.250 · 证据 1 条
  • YBX1 综合评分: 0.244 · 证据 1 条
  • MSI1 综合评分: 0.212 · 证据 1 条
  • TFIP11 综合评分: 0.212 · 证据 1 条
  • EIF4A3 综合评分: 0.162 · 证据 2 条
  • UPF1 综合评分: 0.162 · 证据 1 条
  • ACIN1 综合评分: 0.150 · 证据 2 条
  • U2af1 综合评分: 0.150 · 证据 1 条
  • ELAVL3 综合评分: 0.100 · 证据 1 条
🏥 关联疾病

该基因暂无关联疾病记录

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