🧬 基因注释：ALOX12
📝 官方信息
官方名称：arachidonate 12-lipoxygenase, 12S type
功能摘要：This gene encodes a member of the lipoxygenase family of proteins. The encoded enzyme acts on different polyunsaturated fatty acid substrates to generate bioactive lipid mediators including eicosanoids and lipoxins. The encoded enzyme and its reaction products have been shown to regulate platelet function. Elevated expression of this gene has been observed in pancreatic islets derived from human diabetes patients. Allelic variants in this gene may be associated with susceptibility to toxoplasmosis. Multiple pseudogenes of this gene have been identified in the human genome. [provided by RefSeq, Aug 2017].
🎯 作为靶基因的剪接因子
- U2af2 置信度: 1.0
🏥 关联疾病
该基因暂无关联疾病记录