SpliceAtlasDB
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🧬 基因注释:ANAPC4

📝 官方信息

官方名称:anaphase promoting complex subunit 4

功能摘要:A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The exact function of this gene product is not known. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013].

🎯 作为靶基因的剪接因子
  • HNRNPC 综合评分: 0.474 · 证据 2 条
  • HNRNPM 综合评分: 0.474 · 证据 2 条
  • HNRNPA1 综合评分: 0.412 · 证据 2 条
  • HNRNPA2B1 综合评分: 0.412 · 证据 2 条
  • HNRNPH1 综合评分: 0.412 · 证据 2 条
  • RBFOX2 综合评分: 0.398 · 证据 2 条
  • FUS 综合评分: 0.362 · 证据 1 条
  • PTBP1 综合评分: 0.362 · 证据 2 条
  • fus 综合评分: 0.362 · 证据 1 条
  • Tardbp 综合评分: 0.346 · 证据 1 条
  • HNRNPL 综合评分: 0.300 · 证据 2 条
  • HNRNPU 综合评分: 0.300 · 证据 2 条
  • KHSRP 综合评分: 0.300 · 证据 2 条
  • SRSF2 综合评分: 0.300 · 证据 1 条
  • Srsf2 综合评分: 0.300 · 证据 1 条
  • MATR3 综合评分: 0.262 · 证据 1 条
  • PCBP2 综合评分: 0.262 · 证据 1 条
  • EWSR1 综合评分: 0.250 · 证据 2 条
  • FUBP1 综合评分: 0.250 · 证据 2 条
  • RBM10 综合评分: 0.250 · 证据 2 条
🏥 关联疾病

该基因暂无关联疾病记录

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