🧬 基因注释：ANGPTL3
📝 官方信息
官方名称：angiopoietin like 3
功能摘要：This gene encodes a member of a family of secreted proteins that function in angiogenesis. The encoded protein, which is expressed predominantly in the liver, is further processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metabolism, while the C-terminal chain may be involved in angiogenesis. Mutations in this gene cause familial hypobetalipoproteinemia type 2. [provided by RefSeq, Aug 2015].
🎯 作为靶基因的剪接因子
- PCBP2 置信度: 1.0
🏥 关联疾病
该基因暂无关联疾病记录