基因注释：ANGPTL3

官方名称：angiopoietin like 3

功能摘要：This gene encodes a member of a family of secreted proteins that function in angiogenesis. The encoded protein, which is expressed predominantly in the liver, is further processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metabolism, while the C-terminal chain may be involved in angiogenesis. Mutations in this gene cause familial hypobetalipoproteinemia type 2. [provided by RefSeq, Aug 2015].

• PCBP2 综合评分: 0.262 · 证据 1 条

该基因暂无关联疾病记录