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🧬 基因注释:APLN

📝 官方信息

官方名称:apelin

功能摘要:This gene encodes a peptide that functions as an endogenous ligand for the G-protein coupled apelin receptor. The encoded preproprotein is proteolytically processed into biologically active C-terminal peptide fragments. These peptide fragments activate different tissue specific signaling pathways that regulate diverse biological functions including fluid homeostasis, cardiovascular function and insulin secretion. This protein also functions as a coreceptor for the human immunodeficiency virus 1. [provided by RefSeq, Feb 2016].

🎯 作为靶基因的剪接因子
  • MBNL1 综合评分: 0.350 · 证据 2 条
  • MBNL2 综合评分: 0.298 · 证据 1 条
  • Mbnl2 综合评分: 0.262 · 证据 1 条
  • Ptbp2 综合评分: 0.200 · 证据 1 条
  • NXF1 综合评分: 0.100 · 证据 1 条
  • YBX1 综合评分: 0.100 · 证据 1 条
🏥 关联疾病

该基因暂无关联疾病记录

🔗 外部数据库链接