🧬 基因注释：APLNR
📝 官方信息
官方名称：apelin receptor
功能摘要：This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified. [provided by RefSeq, Jul 2009].
🎯 作为靶基因的剪接因子
- MBNL2 综合评分: 0.200 · 证据 1 条
🏥 关联疾病
该基因暂无关联疾病记录