🧬 基因注释:ARF4
官方名称:ARF GTPase 4
功能摘要:This gene is a member of the human ARF gene family whose members encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The gene products include 5 ARF proteins and 11 ARF-like proteins and constitute one family of the RAS superfamily. The ARF proteins are categorized as class I, class II and class III; this gene is a class II member. The members of each class share a common gene organization. The ARF4 gene spans approximately 12kb and contains six exons and five introns. This gene is the most divergent member of the human ARFs. Conflicting map positions at 3p14 or 3p21 have been reported for this gene. [provided by RefSeq, Jul 2008].
- RBFOX2 综合评分: 0.506 · 证据 2 条
- FUS 综合评分: 0.486 · 证据 1 条
- fus 综合评分: 0.486 · 证据 1 条
- Srsf3 综合评分: 0.424 · 证据 1 条
- HNRNPA1 综合评分: 0.412 · 证据 2 条
- HNRNPA2B1 综合评分: 0.412 · 证据 2 条
- HNRNPC 综合评分: 0.412 · 证据 2 条
- PTBP1 综合评分: 0.362 · 证据 2 条
- MBNL1 综合评分: 0.350 · 证据 2 条
- FUBP1 综合评分: 0.348 · 证据 2 条
- ELAVL3 综合评分: 0.329 · 证据 1 条
- PCBP2 综合评分: 0.324 · 证据 1 条
- UPF1 综合评分: 0.306 · 证据 1 条
- HNRNPK 综合评分: 0.300 · 证据 2 条
- HNRNPL 综合评分: 0.300 · 证据 2 条
- HNRNPU 综合评分: 0.300 · 证据 2 条
- SRSF3 综合评分: 0.300 · 证据 1 条
- SRSF9 综合评分: 0.300 · 证据 1 条
- MBNL2 综合评分: 0.262 · 证据 1 条
- Mbnl2 综合评分: 0.262 · 证据 1 条
该基因暂无关联疾病记录