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🧬 基因注释:ARG2

📝 官方信息

官方名称:arginase 2

功能摘要:Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described. [provided by RefSeq, Jul 2008].

🎯 作为靶基因的剪接因子
  • HNRNPA1 综合评分: 0.350 · 证据 2 条
  • HNRNPU 综合评分: 0.300 · 证据 2 条
  • RBFOX2 综合评分: 0.300 · 证据 2 条
  • RBM10 综合评分: 0.250 · 证据 2 条
  • TIA1 综合评分: 0.250 · 证据 1 条
  • Tardbp 综合评分: 0.248 · 证据 1 条
  • CPSF6 综合评分: 0.212 · 证据 2 条
  • PRPF8 综合评分: 0.200 · 证据 1 条
  • CSTF2T 综合评分: 0.162 · 证据 2 条
  • PABPC4 综合评分: 0.150 · 证据 2 条
  • PRPF4 综合评分: 0.150 · 证据 1 条
  • Srsf1 综合评分: 0.150 · 证据 1 条
  • U2af1 综合评分: 0.150 · 证据 1 条
  • Rbmx 综合评分: 0.100 · 证据 1 条
  • Rbpms 综合评分: 0.100 · 证据 1 条
  • Tra2a 综合评分: 0.100 · 证据 1 条
  • U2af2 综合评分: 0.100 · 证据 1 条
  • UPF1 综合评分: 0.100 · 证据 1 条
🏥 关联疾病

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