🧬 基因注释：ARHGEF6
📝 官方信息
官方名称：Rac/Cdc42 guanine nucleotide exchange factor 6
功能摘要：Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific cognitive disability. [provided by RefSeq, Jul 2008].
🎯 作为靶基因的剪接因子
- Tardbp 综合评分: 0.398 · 证据 1 条
- FUS 综合评分: 0.362 · 证据 1 条
- PTBP1 综合评分: 0.362 · 证据 2 条
- fus 综合评分: 0.362 · 证据 1 条
- RBM39 综合评分: 0.312 · 证据 2 条
- HNRNPL 综合评分: 0.300 · 证据 2 条
- RBFOX2 综合评分: 0.300 · 证据 2 条
- SRSF2 综合评分: 0.300 · 证据 1 条
- MBNL2 综合评分: 0.262 · 证据 1 条
- PRPF8 综合评分: 0.262 · 证据 1 条
- Ptbp2 综合评分: 0.200 · 证据 1 条
- U2af2 综合评分: 0.162 · 证据 1 条
- CELF2 综合评分: 0.150 · 证据 2 条
- CPSF6 综合评分: 0.150 · 证据 2 条
- Srsf3 综合评分: 0.150 · 证据 1 条
- U2af1 综合评分: 0.150 · 证据 1 条
- ELAVL3 综合评分: 0.100 · 证据 1 条
- Rbpms 综合评分: 0.100 · 证据 1 条
- Srsf7 综合评分: 0.100 · 证据 1 条
- Tra2a 综合评分: 0.100 · 证据 1 条
🏥 关联疾病
该基因暂无关联疾病记录