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🧬 基因注释:ARPC1B

📝 官方信息

官方名称:actin related protein 2/3 complex subunit 1B

功能摘要:This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. This protein also has a role in centrosomal homeostasis by being an activator and substrate of the Aurora A kinase. [provided by RefSeq, Mar 2011].

🎯 作为靶基因的剪接因子
  • HNRNPC 综合评分: 0.448 · 证据 2 条
  • HNRNPA2B1 综合评分: 0.412 · 证据 2 条
  • HNRNPK 综合评分: 0.398 · 证据 2 条
  • Tardbp 综合评分: 0.386 · 证据 1 条
  • RBFOX2 综合评分: 0.362 · 证据 2 条
  • HNRNPH1 综合评分: 0.350 · 证据 2 条
  • MBNL1 综合评分: 0.350 · 证据 2 条
  • TIA1 综合评分: 0.312 · 证据 1 条
  • FUS 综合评分: 0.300 · 证据 1 条
  • fus 综合评分: 0.300 · 证据 1 条
  • RBM39 综合评分: 0.250 · 证据 2 条
  • PCBP2 综合评分: 0.200 · 证据 1 条
  • PRPF8 综合评分: 0.200 · 证据 1 条
  • SF3A3 综合评分: 0.200 · 证据 1 条
  • CSTF2T 综合评分: 0.198 · 证据 2 条
  • YBX1 综合评分: 0.198 · 证据 1 条
  • Rnps1 综合评分: 0.162 · 证据 1 条
  • U2af2 综合评分: 0.162 · 证据 1 条
  • ACIN1 综合评分: 0.150 · 证据 2 条
  • AQR 综合评分: 0.150 · 证据 1 条
🏥 关联疾病

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