🧬 基因注释：ASB2
📝 官方信息
官方名称：ankyrin repeat and SOCS box containing 2
功能摘要：This gene encodes a member of the ankyrin repeat and SOCS box-containing (ASB) protein family. These proteins play a role in protein degradation by coupling suppressor of cytokine signalling (SOCS) proteins with the elongin BC complex. The encoded protein is a subunit of a multimeric E3 ubiquitin ligase complex that mediates the degradation of actin-binding proteins. This gene plays a role in retinoic acid-induced growth inhibition and differentiation of myeloid leukemia cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011].
🎯 作为靶基因的剪接因子
- HNRNPL 置信度: 2.0
🏥 关联疾病
该基因暂无关联疾病记录