🧬 基因注释：ASGR1

官方名称：asialoglycoprotein receptor 1

功能摘要：This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the more abundant major subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011].

• HNRNPC 综合评分: 0.412 · 证据 2 条
• FUS 综合评分: 0.362 · 证据 1 条
• HNRNPK 综合评分: 0.362 · 证据 2 条
• KHSRP 综合评分: 0.362 · 证据 2 条
• SRSF9 综合评分: 0.362 · 证据 1 条
• fus 综合评分: 0.362 · 证据 1 条
• HNRNPM 综合评分: 0.350 · 证据 2 条
• TIA1 综合评分: 0.312 · 证据 1 条
• Tardbp 综合评分: 0.310 · 证据 1 条
• RBFOX2 综合评分: 0.300 · 证据 2 条
• PCBP1 综合评分: 0.262 · 证据 2 条
• PCBP2 综合评分: 0.262 · 证据 1 条
• PRPF8 综合评分: 0.262 · 证据 1 条
• AQR 综合评分: 0.212 · 证据 1 条
• PRPF4 综合评分: 0.212 · 证据 1 条
• Srsf1 综合评分: 0.212 · 证据 1 条
• U2af1 综合评分: 0.212 · 证据 1 条
• SF3A3 综合评分: 0.200 · 证据 1 条
• CSTF2T 综合评分: 0.162 · 证据 2 条
• PABPN1 综合评分: 0.162 · 证据 1 条

该基因暂无关联疾病记录