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🧬 基因注释:ATP5PF

📝 官方信息

官方名称:ATP synthase peripheral stalk subunit F6

功能摘要:Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, which comprises the proton channel. The F1 complex consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled in a ratio of 3 alpha, 3 beta, and a single representative of the other 3. The Fo complex has nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the F6 subunit of the Fo complex. The F6 subunit is required for F1 and Fo interactions. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. This gene has 1 or more pseudogenes. [provided by RefSeq, Feb 2016].

🎯 作为靶基因的剪接因子
  • HNRNPC 综合评分: 0.474 · 证据 2 条
  • FUS 综合评分: 0.460 · 证据 1 条
  • fus 综合评分: 0.460 · 证据 1 条
  • HNRNPA2B1 综合评分: 0.412 · 证据 2 条
  • RBFOX2 综合评分: 0.398 · 证据 2 条
  • KHSRP 综合评分: 0.300 · 证据 2 条
  • PTBP1 综合评分: 0.300 · 证据 2 条
  • SRSF9 综合评分: 0.300 · 证据 1 条
  • PRPF8 综合评分: 0.298 · 证据 1 条
  • CSTF2 综合评分: 0.274 · 证据 2 条
  • Tardbp 综合评分: 0.274 · 证据 1 条
  • EWSR1 综合评分: 0.250 · 证据 2 条
  • RBM10 综合评分: 0.250 · 证据 2 条
  • RBM15 综合评分: 0.250 · 证据 2 条
  • RBM22 综合评分: 0.250 · 证据 2 条
  • U2af2 综合评分: 0.224 · 证据 1 条
  • CPSF6 综合评分: 0.212 · 证据 2 条
  • PCBP2 综合评分: 0.200 · 证据 1 条
  • CSTF2T 综合评分: 0.162 · 证据 2 条
  • FUBP3 综合评分: 0.162 · 证据 2 条
🏥 关联疾病

该基因暂无关联疾病记录

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