SpliceAtlasDB
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🧬 基因注释:AURKA

📝 官方信息

官方名称:aurora kinase A

功能摘要:The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].

🎯 作为靶基因的剪接因子
  • Tardbp 综合评分: 0.496 · 证据 1 条
  • FUS 综合评分: 0.460 · 证据 1 条
  • fus 综合评分: 0.460 · 证据 1 条
  • HNRNPA2B1 综合评分: 0.412 · 证据 2 条
  • HNRNPH1 综合评分: 0.412 · 证据 2 条
  • HNRNPA1 综合评分: 0.350 · 证据 2 条
  • HNRNPC 综合评分: 0.350 · 证据 2 条
  • HNRNPM 综合评分: 0.350 · 证据 2 条
  • QKI 综合评分: 0.350 · 证据 1 条
  • EWSR1 综合评分: 0.348 · 证据 2 条
  • RBM10 综合评分: 0.312 · 证据 2 条
  • HNRNPL 综合评分: 0.300 · 证据 2 条
  • HNRNPU 综合评分: 0.300 · 证据 2 条
  • KHSRP 综合评分: 0.300 · 证据 2 条
  • PTBP1 综合评分: 0.300 · 证据 2 条
  • RBFOX2 综合评分: 0.300 · 证据 2 条
  • SRSF9 综合评分: 0.300 · 证据 1 条
  • PRPF8 综合评分: 0.298 · 证据 1 条
  • Rbmx 综合评分: 0.286 · 证据 1 条
  • UPF1 综合评分: 0.260 · 证据 1 条
🏥 关联疾病

该基因暂无关联疾病记录

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