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🧬 基因注释:AURKC

📝 官方信息

官方名称:aurora kinase C

功能摘要:This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008].

🎯 作为靶基因的剪接因子
  • HNRNPA2B1 综合评分: 0.412 · 证据 2 条
  • PTBP1 综合评分: 0.362 · 证据 2 条
  • RBM10 综合评分: 0.250 · 证据 2 条
  • U2af1 综合评分: 0.212 · 证据 1 条
  • PCBP2 综合评分: 0.200 · 证据 1 条
  • Rbmx 综合评分: 0.100 · 证据 1 条
🏥 关联疾病

该基因暂无关联疾病记录

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