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🧬 基因注释:AIMP1

📝 官方信息

官方名称:aminoacyl tRNA synthetase complex interacting multifunctional protein 1

功能摘要:The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20. [provided by RefSeq, Dec 2008].

🎯 作为靶基因的剪接因子
  • HNRNPC 综合评分: 0.510 · 证据 2 条
  • HNRNPH1 综合评分: 0.474 · 证据 2 条
  • RBFOX2 综合评分: 0.460 · 证据 2 条
  • HNRNPA1 综合评分: 0.448 · 证据 2 条
  • HNRNPA2B1 综合评分: 0.412 · 证据 2 条
  • Tardbp 综合评分: 0.398 · 证据 1 条
  • HNRNPD 综合评分: 0.362 · 证据 2 条
  • HNRNPU 综合评分: 0.362 · 证据 2 条
  • SRSF2 综合评分: 0.362 · 证据 1 条
  • HNRNPM 综合评分: 0.350 · 证据 2 条
  • PRPF8 综合评分: 0.324 · 证据 1 条
  • RBM10 综合评分: 0.312 · 证据 2 条
  • FUS 综合评分: 0.300 · 证据 1 条
  • HNRNPK 综合评分: 0.300 · 证据 2 条
  • HNRNPL 综合评分: 0.300 · 证据 2 条
  • KHSRP 综合评分: 0.300 · 证据 2 条
  • PTBP1 综合评分: 0.300 · 证据 2 条
  • SRSF3 综合评分: 0.300 · 证据 1 条
  • SRSF9 综合评分: 0.300 · 证据 1 条
  • Srsf2 综合评分: 0.300 · 证据 1 条
🏥 关联疾病

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