🧬 基因注释：ATG4D

官方名称：autophagy related 4D cysteine peptidase

功能摘要：Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene belongs to the autophagy-related protein 4 (Atg4) family of C54 endopeptidases. Members of this family encode proteins that play a role in the biogenesis of autophagosomes, which sequester the cytosol and organelles for degradation by lysosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013].

• HNRNPC 综合评分: 0.474 · 证据 2 条
• HNRNPK 综合评分: 0.398 · 证据 2 条
• TIA1 综合评分: 0.312 · 证据 1 条
• RBM10 综合评分: 0.250 · 证据 2 条
• RBM22 综合评分: 0.250 · 证据 2 条
• GRSF1 综合评分: 0.212 · 证据 2 条
• PRPF8 综合评分: 0.200 · 证据 1 条
• AQR 综合评分: 0.150 · 证据 1 条
• CPSF6 综合评分: 0.150 · 证据 2 条
• PABPC4 综合评分: 0.150 · 证据 2 条
• Srsf2 综合评分: 0.150 · 证据 1 条
• Srsf4 综合评分: 0.150 · 证据 1 条
• EIF4A3 综合评分: 0.100 · 证据 2 条
• NXF1 综合评分: 0.100 · 证据 1 条
• Rbmx 综合评分: 0.100 · 证据 1 条
• Rbpms 综合评分: 0.100 · 证据 1 条
• Rnps1 综合评分: 0.100 · 证据 1 条
• U2af2 综合评分: 0.100 · 证据 1 条
• UPF1 综合评分: 0.100 · 证据 1 条
• YBX1 综合评分: 0.100 · 证据 1 条

该基因暂无关联疾病记录