🧬 基因注释：ATP23
📝 官方信息
官方名称：ATP23 metallopeptidase and ATP synthase assembly factor homolog
功能摘要：The protein encoded by this gene is amplified in glioblastomas and interacts with the DNA binding subunit of DNA-dependent protein kinase. This kinase is involved in double-strand break repair (DSB), and higher expression of the encoded protein increases the efficiency of DSB. In addition, comparison to orthologous proteins strongly suggests that this protein is a metalloprotease important in the biosynthesis of mitochondrial ATPase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016].
🏥 关联疾病
该基因暂无关联疾病记录