🧬 基因注释：ATP6V0C

官方名称：ATPase H+ transporting V0 subunit c

功能摘要：This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c', and d. This gene encodes the V0 subunit c. Alternative splicing results in transcript variants. Pseudogenes have been identified on chromosomes 6 and 17. [provided by RefSeq, Nov 2010].

• HNRNPC 综合评分: 0.494 · 证据 2 条
• Nova2 综合评分: 0.458 · 证据 1 条
• MBNL2 综合评分: 0.436 · 证据 1 条
• Srsf3 综合评分: 0.424 · 证据 1 条
• HNRNPA2B1 综合评分: 0.412 · 证据 2 条
• HNRNPM 综合评分: 0.412 · 证据 2 条
• PTBP1 综合评分: 0.398 · 证据 2 条
• HNRNPK 综合评分: 0.362 · 证据 2 条
• RBFOX2 综合评分: 0.362 · 证据 2 条
• MBNL1 综合评分: 0.350 · 证据 2 条
• CELF2 综合评分: 0.346 · 证据 2 条
• PCBP2 综合评分: 0.324 · 证据 1 条
• Rnps1 综合评分: 0.322 · 证据 1 条
• ELAVL3 综合评分: 0.314 · 证据 1 条
• EWSR1 综合评分: 0.312 · 证据 2 条
• RBM10 综合评分: 0.312 · 证据 2 条
• RBM39 综合评分: 0.312 · 证据 2 条
• TIA1 综合评分: 0.312 · 证据 1 条
• Tardbp 综合评分: 0.310 · 证据 1 条
• FUS 综合评分: 0.300 · 证据 1 条

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