🧬 基因注释：BCL2L11

官方名称：BCL2 like 11

功能摘要：The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Jun 2013].

• SRSF1 综合评分: 0.693 · 证据 1 条
• Srsf1 综合评分: 0.693 · 证据 1 条
• SRSF2 综合评分: 0.586 · 证据 1 条
• Srsf2 综合评分: 0.586 · 证据 2 条
• HNRNPM 综合评分: 0.474 · 证据 2 条
• SF1 综合评分: 0.457 · 证据 2 条
• HNRNPA1 综合评分: 0.407 · 证据 2 条
• HNRNPC 综合评分: 0.407 · 证据 2 条
• HNRNPK 综合评分: 0.362 · 证据 2 条
• KHSRP 综合评分: 0.362 · 证据 2 条
• SRSF3 综合评分: 0.357 · 证据 1 条
• Srsf3 综合评分: 0.357 · 证据 2 条
• HNRNPA2B1 综合评分: 0.350 · 证据 2 条
• MBNL1 综合评分: 0.350 · 证据 2 条
• PRPF8 综合评分: 0.324 · 证据 1 条
• RBM15 综合评分: 0.312 · 证据 2 条
• SRSF11 综合评分: 0.307 · 证据 1 条
• SRSF4 综合评分: 0.307 · 证据 1 条
• SRSF6 综合评分: 0.307 · 证据 1 条
• Srsf4 综合评分: 0.307 · 证据 2 条

该基因暂无关联疾病记录