🧬 基因注释：BEX2
📝 官方信息
官方名称：brain expressed X-linked 2
功能摘要：This gene belongs to the brain expressed X-linked gene family. The encoded protein interacts with the transcription factor LIM domain only 2 in a DNA-binding complex that recognizes the E-box element and promotes transcription. This gene has been found to be a tumor suppressor that is silenced in human glioma. In breast cancer cells, this gene product modulates apoptosis in response to estrogen and tamoxifen, and enhances the anti-proliferative effect of tamoxifen. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009].
🎯 作为靶基因的剪接因子
- CPSF6 置信度: 2.0
- CPSF7 置信度: 2.0
- CSTF2T 置信度: 2.0
- GRSF1 置信度: 2.0
- HNRNPH1 置信度: 2.0
- RBFOX2 置信度: 2.0
- RBM10 置信度: 2.0
- AQR 置信度: 1.0
- ELAVL3 置信度: 1.0
- MBNL2 置信度: 1.0
- Mbnl2 置信度: 1.0
- Rbmx 置信度: 1.0
- SRSF9 置信度: 1.0
- Srsf1 置信度: 1.0
- Srsf3 置信度: 1.0
- Srsf4 置信度: 1.0
- Tardbp 置信度: 1.0
- U2af1 置信度: 1.0
- U2af2 置信度: 1.0
- UPF1 置信度: 1.0
🏥 关联疾病
该基因暂无关联疾病记录