🧬 基因注释：BMX
📝 官方信息
官方名称：BMX non-receptor tyrosine kinase
功能摘要：This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016].
🎯 作为靶基因的剪接因子
- HNRNPA2B1 综合评分: 0.412 · 证据 2 条
- SRSF9 综合评分: 0.362 · 证据 1 条
- FUBP1 综合评分: 0.312 · 证据 2 条
- RBM10 综合评分: 0.312 · 证据 2 条
- TIA1 综合评分: 0.312 · 证据 1 条
- HNRNPU 综合评分: 0.300 · 证据 2 条
- KHSRP 综合评分: 0.300 · 证据 2 条
- RBFOX2 综合评分: 0.300 · 证据 2 条
- MBNL2 综合评分: 0.298 · 证据 1 条
- ELAVL3 综合评分: 0.296 · 证据 1 条
- Rnps1 综合评分: 0.296 · 证据 1 条
- U2af2 综合评分: 0.274 · 证据 1 条
- RBM15 综合评分: 0.250 · 证据 2 条
- CPSF6 综合评分: 0.248 · 证据 2 条
- U2af1 综合评分: 0.248 · 证据 1 条
- CPSF7 综合评分: 0.212 · 证据 2 条
- Tardbp 综合评分: 0.212 · 证据 1 条
- PCBP2 综合评分: 0.200 · 证据 1 条
- PRPF8 综合评分: 0.200 · 证据 1 条
- Tra2a 综合评分: 0.162 · 证据 1 条
🏥 关联疾病
该基因暂无关联疾病记录