🧬 基因注释:BANF1
官方名称:barrier to autointegration nuclear assembly factor 1
功能摘要:The protein encoded by this gene was first identified by its ability to protect retroviruses from intramolecular integration and therefore promote intermolecular integration into the host cell genome. The protein forms a homodimer which localizes to both the nucleus and cytoplasm and is specifically associated with chromosomes during mitosis. This protein binds to double stranded DNA in a non-specific manner and also binds to LEM-domain containing proteins of the nuclear envelope. This protein is thought to facilitate nuclear reassembly by binding with both DNA and inner nuclear membrane proteins and thereby recruit chromatin to the nuclear periphery. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Jan 2009].
- HNRNPC 综合评分: 0.510 · 证据 2 条
- Srsf3 综合评分: 0.460 · 证据 1 条
- HNRNPA2B1 综合评分: 0.412 · 证据 2 条
- Tardbp 综合评分: 0.408 · 证据 1 条
- TIA1 综合评分: 0.374 · 证据 1 条
- HNRNPH1 综合评分: 0.350 · 证据 2 条
- MBNL1 综合评分: 0.350 · 证据 2 条
- FUS 综合评分: 0.300 · 证据 1 条
- HNRNPK 综合评分: 0.300 · 证据 2 条
- PTBP1 综合评分: 0.300 · 证据 2 条
- RBFOX2 综合评分: 0.300 · 证据 2 条
- SRSF3 综合评分: 0.300 · 证据 1 条
- fus 综合评分: 0.300 · 证据 1 条
- PRPF8 综合评分: 0.298 · 证据 1 条
- UPF1 综合评分: 0.286 · 证据 1 条
- ELAVL3 综合评分: 0.274 · 证据 1 条
- Ptbp2 综合评分: 0.262 · 证据 1 条
- Rnps1 综合评分: 0.260 · 证据 1 条
- RBM15 综合评分: 0.250 · 证据 2 条
- U2af1 综合评分: 0.248 · 证据 1 条
该基因暂无关联疾病记录