🧬 基因注释：BMI1

官方名称：BMI1 proto-oncogene, polycomb ring finger

功能摘要：This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene. [provided by RefSeq, Sep 2015].

• HNRNPC 综合评分: 0.474 · 证据 2 条
• FUS 综合评分: 0.362 · 证据 1 条
• HNRNPD 综合评分: 0.362 · 证据 2 条
• KHSRP 综合评分: 0.362 · 证据 2 条
• RBFOX2 综合评分: 0.362 · 证据 2 条
• fus 综合评分: 0.362 · 证据 1 条
• HNRNPA2B1 综合评分: 0.350 · 证据 2 条
• HNRNPM 综合评分: 0.350 · 证据 2 条
• MBNL1 综合评分: 0.350 · 证据 2 条
• FUBP1 综合评分: 0.348 · 证据 2 条
• TIA1 综合评分: 0.312 · 证据 1 条
• PTBP1 综合评分: 0.300 · 证据 2 条
• PRPF8 综合评分: 0.298 · 证据 1 条
• ELAVL3 综合评分: 0.274 · 证据 1 条
• EWSR1 综合评分: 0.250 · 证据 2 条
• RBM10 综合评分: 0.250 · 证据 2 条
• RBM15 综合评分: 0.250 · 证据 2 条
• RBM39 综合评分: 0.250 · 证据 2 条
• Srsf1 综合评分: 0.248 · 证据 1 条
• Tardbp 综合评分: 0.248 · 证据 1 条

该基因暂无关联疾病记录