基因注释 - C1ORF56

📝 官方信息

官方名称：chromosome 1 open reading frame 56

功能摘要：This gene is a proto-oncogene whose promoter is methylated by DNA methyltransferase 3B (DNMT3B), which represses the proto-oncogene. However, a catalytically inactive isoform of DNMT3B is overexpressed in lymphomas, leading to hypomethylation of the proto-oncogene's promoter and derepression of the proto-oncogene. [provided by RefSeq, Sep 2016].

🎯 作为靶基因的剪接因子

PCBP2 综合评分: 0.262 · 证据 1 条
RBM15 综合评分: 0.250 · 证据 2 条
Rbmx 综合评分: 0.162 · 证据 1 条
MSI1 综合评分: 0.150 · 证据 1 条
CSTF2T 综合评分: 0.100 · 证据 2 条
Rnps1 综合评分: 0.100 · 证据 1 条

🏥 关联疾病

该基因暂无关联疾病记录

🔗 外部数据库链接

NCBI Gene GenBank Ensembl GeneCards UniProt

🧬 基因注释：C1ORF56