🧬 基因注释：CARD11
官方名称：caspase recruitment domain family member 11
功能摘要：The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq, Jul 2008].
- CELF2 置信度: 2.0
- CPSF6 置信度: 2.0
- CSTF2T 置信度: 2.0
- HNRNPA1 置信度: 2.0
- HNRNPC 置信度: 2.0
- HNRNPK 置信度: 2.0
- HNRNPL 置信度: 2.0
- HNRNPM 置信度: 2.0
- HNRNPU 置信度: 2.0
- PTBP1 置信度: 2.0
- RBFOX2 置信度: 2.0
- RBM22 置信度: 2.0
- CPSF1 置信度: 1.0
- MATR3 置信度: 1.0
- PRPF8 置信度: 1.0
- SRSF3 置信度: 1.0
- Srsf1 置信度: 1.0
- Tardbp 置信度: 1.0
- Tra2a 置信度: 1.0
- U2af1 置信度: 1.0
该基因暂无关联疾病记录