🧬 基因注释：CBFA2T3
📝 官方信息
官方名称：CBFA2/RUNX1 partner transcriptional co-repressor 3
功能摘要：This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010].
🎯 作为靶基因的剪接因子
- HNRNPA1 综合评分: 0.448 · 证据 2 条
- FUS 综合评分: 0.362 · 证据 1 条
- HNRNPK 综合评分: 0.362 · 证据 2 条
- HNRNPL 综合评分: 0.362 · 证据 2 条
- fus 综合评分: 0.362 · 证据 1 条
- HNRNPC 综合评分: 0.350 · 证据 2 条
- HNRNPM 综合评分: 0.350 · 证据 2 条
- RBM10 综合评分: 0.312 · 证据 2 条
- HNRNPU 综合评分: 0.300 · 证据 2 条
- PTBP1 综合评分: 0.300 · 证据 2 条
- RBFOX2 综合评分: 0.300 · 证据 2 条
- RBM15 综合评分: 0.250 · 证据 2 条
- RBM39 综合评分: 0.250 · 证据 2 条
- U2af2 综合评分: 0.244 · 证据 1 条
- DDX5 综合评分: 0.212 · 证据 2 条
- Srsf1 综合评分: 0.212 · 证据 1 条
- Tardbp 综合评分: 0.212 · 证据 1 条
- Nova2 综合评分: 0.200 · 证据 1 条
- PCBP1 综合评分: 0.200 · 证据 2 条
- PRPF8 综合评分: 0.200 · 证据 1 条
🏥 关联疾病
该基因暂无关联疾病记录