🧬 基因注释：CBX1

官方名称：chromobox 1

功能摘要：This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008].

• HNRNPH1 综合评分: 0.474 · 证据 2 条
• RBFOX2 综合评分: 0.460 · 证据 2 条
• HNRNPA1 综合评分: 0.412 · 证据 2 条
• HNRNPA2B1 综合评分: 0.412 · 证据 2 条
• FUS 综合评分: 0.398 · 证据 1 条
• HNRNPL 综合评分: 0.398 · 证据 2 条
• fus 综合评分: 0.398 · 证据 1 条
• Tardbp 综合评分: 0.379 · 证据 1 条
• KHSRP 综合评分: 0.362 · 证据 2 条
• Srsf2 综合评分: 0.362 · 证据 1 条
• HNRNPC 综合评分: 0.350 · 证据 2 条
• HNRNPM 综合评分: 0.350 · 证据 2 条
• QKI 综合评分: 0.350 · 证据 1 条
• EWSR1 综合评分: 0.348 · 证据 2 条
• PRPF8 综合评分: 0.324 · 证据 1 条
• RBM10 综合评分: 0.312 · 证据 2 条
• TIA1 综合评分: 0.312 · 证据 1 条
• U2af2 综合评分: 0.306 · 证据 1 条
• HNRNPU 综合评分: 0.300 · 证据 2 条
• SRSF2 综合评分: 0.300 · 证据 1 条

该基因暂无关联疾病记录