🧬 基因注释：CBX5

官方名称：chromobox 5

功能摘要：This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008].

• HNRNPC 综合评分: 0.592 · 证据 2 条
• PTBP1 综合评分: 0.486 · 证据 2 条
• FUS 综合评分: 0.460 · 证据 1 条
• fus 综合评分: 0.460 · 证据 1 条
• Srsf3 综合评分: 0.444 · 证据 1 条
• Tardbp 综合评分: 0.426 · 证据 1 条
• HNRNPA2B1 综合评分: 0.412 · 证据 2 条
• MBNL2 综合评分: 0.360 · 证据 1 条
• PCBP2 综合评分: 0.360 · 证据 1 条
• HNRNPA1 综合评分: 0.350 · 证据 2 条
• HNRNPH1 综合评分: 0.350 · 证据 2 条
• HNRNPM 综合评分: 0.350 · 证据 2 条
• MBNL1 综合评分: 0.350 · 证据 2 条
• ELAVL3 综合评分: 0.336 · 证据 1 条
• EWSR1 综合评分: 0.312 · 证据 2 条
• HNRNPD 综合评分: 0.300 · 证据 2 条
• HNRNPK 综合评分: 0.300 · 证据 2 条
• HNRNPL 综合评分: 0.300 · 证据 2 条
• HNRNPU 综合评分: 0.300 · 证据 2 条
• KHSRP 综合评分: 0.300 · 证据 2 条

该基因暂无关联疾病记录