🧬 基因注释：CCR2
📝 官方信息
官方名称：C-C motif chemokine receptor 2
功能摘要：The protein encoded by this gene is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. This gene is located in the chemokine receptor gene cluster region of chromosome 3. [provided by RefSeq, Aug 2017].
🎯 作为靶基因的剪接因子
- HNRNPL 置信度: 2.0
🏥 关联疾病
该基因暂无关联疾病记录