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🧬 基因注释:CDC25A

📝 官方信息

官方名称:cell division cycle 25A

功能摘要:CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

🎯 作为靶基因的剪接因子
  • HNRNPM 综合评分: 0.474 · 证据 2 条
  • HNRNPC 综合评分: 0.448 · 证据 2 条
  • FUS 综合评分: 0.398 · 证据 1 条
  • fus 综合评分: 0.398 · 证据 1 条
  • PTBP1 综合评分: 0.362 · 证据 2 条
  • RBFOX2 综合评分: 0.362 · 证据 2 条
  • HNRNPA2B1 综合评分: 0.350 · 证据 2 条
  • RBM10 综合评分: 0.312 · 证据 2 条
  • TIA1 综合评分: 0.312 · 证据 1 条
  • HNRNPL 综合评分: 0.300 · 证据 2 条
  • HNRNPU 综合评分: 0.300 · 证据 2 条
  • KHSRP 综合评分: 0.300 · 证据 2 条
  • SRSF3 综合评分: 0.300 · 证据 1 条
  • SRSF9 综合评分: 0.300 · 证据 1 条
  • Srsf3 综合评分: 0.300 · 证据 1 条
  • PRPF8 综合评分: 0.262 · 证据 1 条
  • ELAVL3 综合评分: 0.260 · 证据 1 条
  • EWSR1 综合评分: 0.250 · 证据 2 条
  • RBM15 综合评分: 0.250 · 证据 2 条
  • Rbmx 综合评分: 0.244 · 证据 1 条
🏥 关联疾病

该基因暂无关联疾病记录

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