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🧬 基因注释:CDC40

📝 官方信息

官方名称:cell division cycle 40

功能摘要:Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp17 protein, which functions in two different cellular processes: pre-mRNA splicing and cell cycle progression. It suggests that this protein may play a role in cell cycle progression. [provided by RefSeq, Jul 2008].

🎯 作为靶基因的剪接因子
  • HNRNPA2B1 综合评分: 0.412 · 证据 2 条
  • HNRNPC 综合评分: 0.350 · 证据 2 条
  • QKI 综合评分: 0.350 · 证据 1 条
  • FUS 综合评分: 0.300 · 证据 1 条
  • HNRNPD 综合评分: 0.300 · 证据 2 条
  • HNRNPU 综合评分: 0.300 · 证据 2 条
  • KHSRP 综合评分: 0.300 · 证据 2 条
  • PTBP1 综合评分: 0.300 · 证据 2 条
  • SRSF2 综合评分: 0.300 · 证据 1 条
  • Srsf2 综合评分: 0.300 · 证据 1 条
  • fus 综合评分: 0.300 · 证据 1 条
  • PRPF8 综合评分: 0.262 · 证据 1 条
  • EWSR1 综合评分: 0.250 · 证据 2 条
  • FUBP1 综合评分: 0.250 · 证据 2 条
  • RBM10 综合评分: 0.250 · 证据 2 条
  • RBM15 综合评分: 0.250 · 证据 2 条
  • RBM39 综合评分: 0.250 · 证据 2 条
  • Nova2 综合评分: 0.200 · 证据 1 条
  • Ptbp2 综合评分: 0.200 · 证据 1 条
  • Rbmx 综合评分: 0.198 · 证据 1 条
🏥 关联疾病
neurodegenerative disease
中关联 (0.464)
dengue disease
低关联 (0.370)
pontocerebellar hypoplasia, type 15
低关联 (0.363)
pontocerebellar hypoplasia
低关联 (0.259)
Non-syndromic pontocerebellar hypoplasia
低关联 (0.259)
respiratory tract infectious disorder
低关联 (0.257)
bile duct disorder
低关联 (0.110)
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