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🧬 基因注释:CDH11

📝 官方信息

官方名称:cadherin 11

功能摘要:This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. [provided by RefSeq, Jul 2008].

🎯 作为靶基因的剪接因子
  • FUS 综合评分: 0.486 · 证据 1 条
  • fus 综合评分: 0.486 · 证据 1 条
  • HNRNPA2B1 综合评分: 0.412 · 证据 2 条
  • MBNL1 综合评分: 0.350 · 证据 2 条
  • RBFOX2 综合评分: 0.300 · 证据 2 条
  • Nova2 综合评分: 0.262 · 证据 1 条
  • Tardbp 综合评分: 0.212 · 证据 1 条
  • MBNL2 综合评分: 0.200 · 证据 1 条
  • Mbnl2 综合评分: 0.200 · 证据 1 条
  • NOVA1 综合评分: 0.200 · 证据 2 条
  • Ptbp2 综合评分: 0.200 · 证据 1 条
  • MSI1 综合评分: 0.150 · 证据 1 条
  • ELAVL3 综合评分: 0.100 · 证据 1 条
  • RBM20 综合评分: 0.100 · 证据 2 条
  • YBX1 综合评分: 0.100 · 证据 1 条
🏥 关联疾病

该基因暂无关联疾病记录

🔗 外部数据库链接