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🧬 基因注释:CETN3

📝 官方信息

官方名称:centrin 3

功能摘要:The protein encoded by this gene contains four EF-hand calcium binding domains, and is a member of the centrin protein family. Centrins are evolutionarily conserved proteins similar to the CDC31 protein of S. cerevisiae. Yeast CDC31 is located at the centrosome of interphase and mitotic cells, where it plays a fundamental role in centrosome duplication and separation. Multiple forms of the proteins similar to the yeast centrin have been identified in human and other mammalian cells, some of which have been shown to be associated with centrosome fractions. This protein appears to be one of the most abundant centrins associated with centrosome, which suggests a similar function to its yeast counterpart. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014].

🎯 作为靶基因的剪接因子
  • KHSRP 综合评分: 0.398 · 证据 2 条
  • PTBP1 综合评分: 0.398 · 证据 2 条
  • RBFOX2 综合评分: 0.398 · 证据 2 条
  • Tardbp 综合评分: 0.386 · 证据 1 条
  • HNRNPL 综合评分: 0.362 · 证据 2 条
  • HNRNPA2B1 综合评分: 0.350 · 证据 2 条
  • FUS 综合评分: 0.300 · 证据 1 条
  • SRSF2 综合评分: 0.300 · 证据 1 条
  • fus 综合评分: 0.300 · 证据 1 条
  • Nova2 综合评分: 0.298 · 证据 1 条
  • PRPF8 综合评分: 0.262 · 证据 1 条
  • Ptbp2 综合评分: 0.262 · 证据 1 条
  • EWSR1 综合评分: 0.250 · 证据 2 条
  • FUBP1 综合评分: 0.250 · 证据 2 条
  • RBM10 综合评分: 0.250 · 证据 2 条
  • RBM15 综合评分: 0.250 · 证据 2 条
  • TIA1 综合评分: 0.250 · 证据 1 条
  • CPSF6 综合评分: 0.212 · 证据 2 条
  • CSTF2 综合评分: 0.212 · 证据 2 条
  • U2af2 综合评分: 0.198 · 证据 1 条
🏥 关联疾病

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