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🧬 基因注释:CHKB

📝 官方信息

官方名称:choline kinase beta

功能摘要:Choline kinase (CK) and ethanolamine kinase (EK) catalyze the phosphorylation of choline/ethanolamine to phosphocholine/phosphoethanolamine. This is the first enzyme in the biosynthesis of phosphatidylcholine/phosphatidylethanolamine in all animal cells. The highly purified CKs from mammalian sources and their recombinant gene products have been shown to have EK activity also, indicating that both activities reside on the same protein. The choline kinase-like protein encoded by CHKL belongs to the choline/ethanolamine kinase family; however, its exact function is not known. Read-through transcripts are expressed from this locus that include exons from the downstream CPT1B locus. [provided by RefSeq, Jun 2009].

🎯 作为靶基因的剪接因子
  • HNRNPC 综合评分: 0.494 · 证据 2 条
  • HNRNPK 综合评分: 0.444 · 证据 2 条
  • HNRNPA2B1 综合评分: 0.412 · 证据 2 条
  • SRSF9 综合评分: 0.362 · 证据 1 条
  • HNRNPH1 综合评分: 0.350 · 证据 2 条
  • PCBP2 综合评分: 0.324 · 证据 1 条
  • RBM10 综合评分: 0.312 · 证据 2 条
  • FUS 综合评分: 0.300 · 证据 1 条
  • RBFOX2 综合评分: 0.300 · 证据 2 条
  • fus 综合评分: 0.300 · 证据 1 条
  • PRPF8 综合评分: 0.298 · 证据 1 条
  • SF3A3 综合评分: 0.262 · 证据 1 条
  • EWSR1 综合评分: 0.250 · 证据 2 条
  • RBM15 综合评分: 0.250 · 证据 2 条
  • TIA1 综合评分: 0.250 · 证据 1 条
  • Srsf1 综合评分: 0.248 · 证据 1 条
  • Srsf3 综合评分: 0.248 · 证据 1 条
  • Rnps1 综合评分: 0.224 · 证据 1 条
  • AQR 综合评分: 0.212 · 证据 1 条
  • GRSF1 综合评分: 0.212 · 证据 2 条
🏥 关联疾病

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