🧬 基因注释：CLDN23
📝 官方信息
官方名称：claudin 23
功能摘要：This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is expressed in germinal center B-cells, placenta and stomach as well as in colon tumor. This gene is down-regulated in intestinal type gastric cancer. [provided by RefSeq, Aug 2010].
🎯 作为靶基因的剪接因子
- YBX1 置信度: 1.0
🏥 关联疾病
该基因暂无关联疾病记录