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🧬 基因注释:COX6C

📝 官方信息

官方名称:cytochrome c oxidase subunit 6C

功能摘要:Cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIc, which has 77% amino acid sequence identity with mouse subunit VIc. This gene is up-regulated in prostate cancer cells. A pseudogene has been found on chromosomes 16p12. [provided by RefSeq, Jul 2010].

🎯 作为靶基因的剪接因子
  • FUS 综合评分: 0.486 · 证据 1 条
  • fus 综合评分: 0.486 · 证据 1 条
  • RBFOX2 综合评分: 0.444 · 证据 2 条
  • HNRNPL 综合评分: 0.424 · 证据 2 条
  • HNRNPC 综合评分: 0.412 · 证据 2 条
  • PTBP1 综合评分: 0.398 · 证据 2 条
  • HNRNPA2B1 综合评分: 0.350 · 证据 2 条
  • HNRNPM 综合评分: 0.350 · 证据 2 条
  • Tardbp 综合评分: 0.324 · 证据 1 条
  • KHSRP 综合评分: 0.300 · 证据 2 条
  • EWSR1 综合评分: 0.250 · 证据 2 条
  • FUBP1 综合评分: 0.250 · 证据 2 条
  • RBM10 综合评分: 0.250 · 证据 2 条
  • RBM15 综合评分: 0.250 · 证据 2 条
  • TIA1 综合评分: 0.250 · 证据 1 条
  • CSTF2 综合评分: 0.212 · 证据 2 条
  • PRPF8 综合评分: 0.200 · 证据 1 条
  • Ptbp2 综合评分: 0.200 · 证据 1 条
  • Rbmx 综合评分: 0.198 · 证据 1 条
  • U2af2 综合评分: 0.162 · 证据 1 条
🏥 关联疾病

该基因暂无关联疾病记录

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