🧬 基因注释：CXCR4
📝 官方信息
官方名称：C-X-C motif chemokine receptor 4
功能摘要：This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
🎯 作为靶基因的剪接因子
- CELF2 置信度: 2.0
- CSTF2 置信度: 2.0
- CSTF2T 置信度: 2.0
- EIF4A3 置信度: 2.0
- HNRNPC 置信度: 2.0
- HNRNPL 置信度: 2.0
- NOVA1 置信度: 2.0
- PTBP1 置信度: 2.0
- ELAVL3 置信度: 1.0
- FUS 置信度: 1.0
- Rbm7 置信度: 1.0
- Rnps1 置信度: 1.0
- SRSF3 置信度: 1.0
- SRSF9 置信度: 1.0
- Srsf3 置信度: 1.0
- Srsf7 置信度: 1.0
- TFIP11 置信度: 1.0
- TIA1 置信度: 1.0
- Tardbp 置信度: 1.0
- U2af1 置信度: 1.0
🏥 关联疾病
该基因暂无关联疾病记录