🧬 基因注释：CXCR4
📝 官方信息
官方名称：C-X-C motif chemokine receptor 4
功能摘要：This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
🎯 作为靶基因的剪接因子
- CELF2 综合评分: 0.398 · 证据 2 条
- HNRNPC 综合评分: 0.350 · 证据 2 条
- FUS 综合评分: 0.300 · 证据 1 条
- HNRNPL 综合评分: 0.300 · 证据 2 条
- PTBP1 综合评分: 0.300 · 证据 2 条
- SRSF3 综合评分: 0.300 · 证据 1 条
- SRSF9 综合评分: 0.300 · 证据 1 条
- Srsf3 综合评分: 0.300 · 证据 1 条
- fus 综合评分: 0.300 · 证据 1 条
- TIA1 综合评分: 0.250 · 证据 1 条
- Tardbp 综合评分: 0.248 · 证据 1 条
- UPF1 综合评分: 0.224 · 证据 1 条
- CSTF2 综合评分: 0.212 · 证据 2 条
- NOVA1 综合评分: 0.200 · 证据 2 条
- Rnps1 综合评分: 0.198 · 证据 1 条
- CSTF2T 综合评分: 0.162 · 证据 2 条
- ELAVL3 综合评分: 0.162 · 证据 1 条
- U2af2 综合评分: 0.162 · 证据 1 条
- TFIP11 综合评分: 0.150 · 证据 1 条
- U2af1 综合评分: 0.150 · 证据 1 条
🏥 关联疾病
该基因暂无关联疾病记录