🧬 基因注释：CD44

官方名称：CD44 molecule (IN blood group)

功能摘要：The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008].

• HNRNPC 综合评分: 0.464 · 证据 2 条
• Srsf2 综合评分: 0.398 · 证据 1 条
• Srsf3 综合评分: 0.398 · 证据 2 条
• SRSF2 综合评分: 0.362 · 证据 1 条
• HNRNPK 综合评分: 0.357 · 证据 2 条
• HNRNPA1 综合评分: 0.350 · 证据 2 条
• HNRNPA2B1 综合评分: 0.350 · 证据 2 条
• HNRNPH1 综合评分: 0.350 · 证据 2 条
• HNRNPM 综合评分: 0.350 · 证据 2 条
• MBNL1 综合评分: 0.350 · 证据 2 条
• QKI 综合评分: 0.350 · 证据 1 条
• SRSF1 综合评分: 0.350 · 证据 1 条
• Srsf1 综合评分: 0.350 · 证据 1 条
• Srsf4 综合评分: 0.348 · 证据 2 条
• Rnps1 综合评分: 0.306 · 证据 1 条
• FUS 综合评分: 0.300 · 证据 1 条
• HNRNPD 综合评分: 0.300 · 证据 2 条
• HNRNPL 综合评分: 0.300 · 证据 2 条
• HNRNPU 综合评分: 0.300 · 证据 2 条
• KHSRP 综合评分: 0.300 · 证据 2 条

该基因暂无关联疾病记录