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🧬 基因注释:CDK7

📝 官方信息

官方名称:cyclin dependent kinase 7

功能摘要:The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle. [provided by RefSeq, Jul 2008].

🎯 作为靶基因的剪接因子
  • HNRNPC 综合评分: 0.448 · 证据 2 条
  • HNRNPM 综合评分: 0.448 · 证据 2 条
  • HNRNPK 综合评分: 0.362 · 证据 2 条
  • Srsf3 综合评分: 0.362 · 证据 1 条
  • MBNL1 综合评分: 0.350 · 证据 2 条
  • FUS 综合评分: 0.300 · 证据 1 条
  • PTBP1 综合评分: 0.300 · 证据 2 条
  • RBFOX2 综合评分: 0.300 · 证据 2 条
  • SRSF3 综合评分: 0.300 · 证据 1 条
  • fus 综合评分: 0.300 · 证据 1 条
  • Ptbp2 综合评分: 0.298 · 证据 1 条
  • PCBP2 综合评分: 0.262 · 证据 1 条
  • EWSR1 综合评分: 0.250 · 证据 2 条
  • CPSF6 综合评分: 0.212 · 证据 2 条
  • Mbnl2 综合评分: 0.200 · 证据 1 条
  • PRPF8 综合评分: 0.200 · 证据 1 条
  • CELF2 综合评分: 0.150 · 证据 2 条
  • CPSF4 综合评分: 0.150 · 证据 2 条
  • CSTF2 综合评分: 0.150 · 证据 2 条
  • Srsf2 综合评分: 0.150 · 证据 1 条
🏥 关联疾病

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