🧬 基因注释：CPSF6
📝 官方信息
官方名称：cleavage and polyadenylation specific factor 6
功能摘要：The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. The cleavage factor complex is composed of four polypeptides. This gene encodes the 68kD subunit. It has a domain organization reminiscent of spliceosomal proteins. [provided by RefSeq, Jul 2008].
🎯 作为靶基因的剪接因子
- HNRNPC 综合评分: 0.494 · 证据 2 条
- Tardbp 综合评分: 0.475 · 证据 1 条
- HNRNPK 综合评分: 0.424 · 证据 2 条
- HNRNPA1 综合评分: 0.412 · 证据 2 条
- HNRNPA2B1 综合评分: 0.412 · 证据 2 条
- HNRNPF 综合评分: 0.412 · 证据 2 条
- EWSR1 综合评分: 0.374 · 证据 2 条
- HNRNPD 综合评分: 0.362 · 证据 2 条
- HNRNPL 综合评分: 0.362 · 证据 2 条
- RBFOX2 综合评分: 0.362 · 证据 2 条
- SRSF2 综合评分: 0.362 · 证据 1 条
- HNRNPM 综合评分: 0.350 · 证据 2 条
- MBNL1 综合评分: 0.350 · 证据 2 条
- QKI 综合评分: 0.350 · 证据 1 条
- MBNL2 综合评分: 0.324 · 证据 1 条
- PCBP2 综合评分: 0.324 · 证据 1 条
- TIA1 综合评分: 0.312 · 证据 1 条
- FUS 综合评分: 0.300 · 证据 1 条
- HNRNPU 综合评分: 0.300 · 证据 2 条
- KHSRP 综合评分: 0.300 · 证据 2 条
🏥 关联疾病
cancer
中关联 (0.577)
Abnormality of the skeletal system
中关联 (0.486)
neurodegenerative disease
中关联 (0.462)
smoking initiation
中关联 (0.446)
hypertension
低关联 (0.387)
osteoarthritis
低关联 (0.384)
myelodysplastic syndrome
低关联 (0.371)
leukemia
低关联 (0.371)
chronic myelogenous leukemia
低关联 (0.370)
dengue disease
低关联 (0.370)